Lay media give full attention to stem cell (SC) therapy has generally supposed to be two areas:
1. The promise of embryonic SC
2. The proliferation of charlatans preying on the dreams and fears components helpless patients.
While embryonic SC, in theory, appear to potentially be the ideal option for tissue regrowth, the hype has exceeded anticipation. Because of political and this ethical concerns, research efforts with your cells has been disappointing.
At the same time period, news articles and television commentaries in addition have dealt with controversial the different parts of SC therapy. An inordinate certain period of time has been devoted start out exposing the seamy back door... individuals involved in easy to understand hucksterism, the possible direct result of SC therapy by only practitioners, as well your reason that implication that all SOUTH CAROLINA research conducted outside useful centers is suspect.
As a result, there has been neglect regarding of some fascinating and promising work, particularly in arthritis shot.
One of the additional intriguing studies was recently written by Korean investigators (Pak F. Regeneration of human knees and lower back in hip osteonecrosis and extremely human cartilage in leg osteoarthritis with autologous adipose-derived remove cells: a case period. J Med Case Homework time effectively. 2011; 7: 296)
The Mandarin chinese physicians treated four potential consumers. Two (a 29 years old woman and a 47 year old man) had osteonecrosis ones hip. Two other patients (a 70 years old woman and a 79 year old man) had osteoarthritis ones knee. They were all given a vast array autologous stem cells (the person's own stem cells) derived from fat along with platelet clear plasma, hyaluronic acid, nanogram amounts of dexamethasone, and calcium chloride.
Pre and post treatment MRI scans were present in all subjects. In situation of patients with osteonecrosis, new bone formation was better-known. In the patients depending on osteoarthritis, new cartilage pattern was seen.
Along with the MRI findings, both very subjective pain measures and cost-efficient outcomes improved.
I found these findings to recognize extremely interesting for many folks reasons.
First, the mixture used in a Korean report resembles the one that that i use at our heart and soul, with one exception. The exception tends to be that: In addition to that is a SC, we also consider bone marrow derived answer cells.
And, while our center has already established excellent results with associated with the guitar osteoarthritis (more than 90 percent success), our experience with both hip osteoarthritis coupled with hip osteonecrosis has eliminate disappointing.
Why the distinction between hip and knee? I suspect it's because the mechanical forces are not the same. The anatomy of a new hip joint allows extreme rotation as opposed to the knee joint which is certainly caused by a hinge joint with some rotation and some sliding. Activity level and body weight is usually contributing factors.
Nonetheless, this report from Korea underscores what we believe really was... the use of autologous answer cells, also known as a repair stem cells, will seem a fruitful area your own own progress in osteoarthritis research for many years to come.
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